MPEP HCl, CAS [[219911-35-0]]

Product Overview

• Article Name: MPEP HCl, CAS [[219911-35-0]]
• Biozol Catalog Number: FBM-10-4007
• Supplier Catalog Number: 10-4007
• Alternative Catalog Number: FBM-10-4007-5MG,FBM-10-4007-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 2-Methyl-6-(2-phenylethynyl)pyridine hydrochloride

Product Description

mGlu5 receptor antagonist

Product Properties

• Molecular Weight: 229.71
• Purity: 98% by HPLC, NMR (Conforms)
• Form: White or pale yellow solid
• CAS Number: [219911-35-0]
• Formula: C14H11NHCl

Application Notes

• Application Notes: MPEP is a potent (IC50 = 36 nM for quisqualate-stimulated phosphoinositide hydrolysis) and selective (over mGlu1b, -2, -3, -4a, -6, -7b, and -8a) antagonist of the metabotropic glutamate receptor subtype 5 (mGlu5).1 It is a positive allosteric modulator of human mGlu4.2 MPEP inhibition of mGlu5 has been studied for the treatment of many CNS disorders including Parkinsons3,4, Fragile X syndrome5, and addiction6.