GSK2879552, CAS [[1401966-69-5]]

Produktübersicht

• Artikelname: GSK2879552, CAS [[1401966-69-5]]
• Artikelnummer: FBM-10-4020
• Hersteller Artikelnummer: 10-4020
• Alternativnummer: FBM-10-4020-5MG, FBM-10-4020-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride

Produktbeschreibung

LSD1 inhibitor

Produkteigenschaften

• Molekulargewicht: 437.40
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1401966-69-5]
• Formel: C23H28N2O2 2HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: GSK289552 is potent, selective, and irreversible inhibitor of Lysine Demethylase 1 (LSD1) via covalent modification of the LSD1 cofactor FAD (Ki = 1.7 µM). It is selective for LSD1 over the closely related LSD2, MAO-A, MAO-B, and the FAD dependent enzymes D-amino acid oxidase and glutathione reductase. Tested against a panel of 165 cancer cell lines, GSK2879552 inhibited the proliferation of 9 small cell lung carcinoma lines and 20 AML cell lines.