LNT 1, CAS [[824983-91-7]]

Artikelnummer: FBM-10-4036
Artikelname: LNT 1, CAS [[824983-91-7]]
Artikelnummer: FBM-10-4036
Hersteller Artikelnummer: 10-4036
Alternativnummer: FBM-10-4036-5MG,FBM-10-4036-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: FEN1-IN-1
FEN1 inhibitor
Molekulargewicht: 332.33
Reinheit: 98% by TLC , NMR (Conforms)
Formulierung: Off-white solid
CAS Nummer: [824983-91-7]
Formel: C15H12N2O5S
Anwendungsbeschreibung: Potent (IC50 = 11 nM) inhibitor of flap endonuclease 1 (FEN1).1 It showed similar potency in inhibiting exonuclease 1 (EXO1).2 Induces a DNA damage response and ultimately cell death. FEN1 inhibitors have therapeutic potential for the treatment of cancers that are defective for homologous repair and other DNA repair and DNA damage checkpoint pathways.4