BZ1, CAS [[2766623-38-3]]

Produktübersicht

• Artikelname: BZ1, CAS [[2766623-38-3]]
• Artikelnummer: FBM-10-4037
• Hersteller Artikelnummer: 10-4037
• Alternativnummer: FBM-10-4037-5MG, FBM-10-4037-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 5-((4-(2-Aminoethyl)phenyl)amino)-4-chloro-2-methylpyridazin-3(2H)-one

Produktbeschreibung

BPTF inhibitor

Produkteigenschaften

• Molekulargewicht: 278.74
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• CAS Nummer: [2766623-38-3]
• Formel: C13H15ClN4O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent (Kd = 6.3 nM, IC50 = 67 nM BPTF Alphascreen) inhibitor of the bromodomain PHD finger transcription factor (BPTF). It displays >350-fold selectivity over BET bromodomains. BZ1 sensitized 4T1 mouse breast cancer cells to doxorubicin treatment. BPTF inhibition represents a potential strategy for the inhibition of nucleosome remodeling factor (NURF) and exploration of its function.