BZ1, CAS [[2766623-38-3]]

Product Overview

• Article Name: BZ1, CAS [[2766623-38-3]]
• Biozol Catalog Number: FBM-10-4037
• Supplier Catalog Number: 10-4037
• Alternative Catalog Number: FBM-10-4037-5MG,FBM-10-4037-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

BPTF inhibitor

Product Properties

• Molecular Weight: 278.74
• Purity: 98% by HPLC NMR (Conforms)
• Form: Yellow solid
• CAS Number: [2766623-38-3]
• Formula: C13H15ClN4O

Application Notes

• Application Notes: Potent (Kd = 6.3 nM, IC50 = 67 nM BPTF Alphascreen) inhibitor of the bromodomain PHD finger transcription factor (BPTF). It displays >350-fold selectivity over BET bromodomains. BZ1 sensitized 4T1 mouse breast cancer cells to doxorubicin treatment. BPTF inhibition represents a potential strategy for the inhibition of nucleosome remodeling factor (NURF) and exploration of its function.