SGC-iMLLT, CAS [[2255338-25-9]]

Produktübersicht

• Artikelname: SGC-iMLLT, CAS [[2255338-25-9]]
• Artikelnummer: FBM-10-4046
• Hersteller Artikelnummer: 10-4046
• Alternativnummer: FBM-10-4046-5MG, FBM-10-4046-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (S)-1-Methyl-N-(2-((2-methylpyrrolidin-1-yl)methyl)-1H-benzo[d]imidazole-5-yl)-1H-indazole-5-carboxamide

Produktbeschreibung

MLLT1/3 YEATS domain inhibitor

Produkteigenschaften

• Molekulargewicht: 388.48
• Reinheit: >98% HPLC, NMR (Conforms)
• Formulierung: Off-white to beige solid
• CAS Nummer: [2255338-25-9]
• Formel: C22H24N6O

Anwendungsbeschreibung

• Anwendungsbeschreibung: Potent (IC50 = 260 nM) inhibitor of the YEATS domain of MLLT1/3.1 YEATS domain containing proteins bind acetyl and crotonyl marks on histone tails. Selective against the two other human YEATS domains YEATS2/4 and 48 bromodomains. YEATS containing MLL-ENL leukemic cells display increased sensitivity to SGC-iMLLT versus control AML cells.2