SGC-iMLLT, CAS [[2255338-25-9]]

Product Overview

• Article Name: SGC-iMLLT, CAS [[2255338-25-9]]
• Biozol Catalog Number: FBM-10-4046
• Supplier Catalog Number: 10-4046
• Alternative Catalog Number: FBM-10-4046-5MG, FBM-10-4046-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: (S)-1-Methyl-N-(2-((2-methylpyrrolidin-1-yl)methyl)-1H-benzo[d]imidazole-5-yl)-1H-indazole-5-carboxamide

Product Description

MLLT1/3 YEATS domain inhibitor

Product Properties

• Molecular Weight: 388.48
• Purity: >98% HPLC, NMR (Conforms)
• Form: Off-white to beige solid
• CAS Number: [2255338-25-9]
• Formula: C22H24N6O

Application Notes

• Application Notes: Potent (IC50 = 260 nM) inhibitor of the YEATS domain of MLLT1/3.1 YEATS domain containing proteins bind acetyl and crotonyl marks on histone tails. Selective against the two other human YEATS domains YEATS2/4 and 48 bromodomains. YEATS containing MLL-ENL leukemic cells display increased sensitivity to SGC-iMLLT versus control AML cells.2