GSK620, CAS [[2088410-46-0]]

Produktübersicht

• Artikelname: GSK620, CAS [[2088410-46-0]]
• Artikelnummer: FBM-10-4047
• Hersteller Artikelnummer: 10-4047
• Alternativnummer: FBM-10-4047-5MG,FBM-10-4047-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-Benzyl-5-N-cyclopropyl-3-N-methyl-2-oxopyridine-3,5-dicarboxamide

Produktbeschreibung

BD2 selective BET inhibitor

Produkteigenschaften

• Molekulargewicht: 325.37
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [2088410-46-0]
• Formel: C18H19N3O3

Anwendungsbeschreibung

• Anwendungsbeschreibung: BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1, BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model and imiquimod-induced psoriasis in a mouse model.2 GSK620 was also able to reduce hepatic fibrosis, steatosis, and inflammation in a mouse model of non-alcoholic steatohepatitis (NASH).

Bilder

10-4047