GSK620, CAS [[2088410-46-0]]

Product Overview

• Article Name: GSK620, CAS [[2088410-46-0]]
• Biozol Catalog Number: FBM-10-4047
• Supplier Catalog Number: 10-4047
• Alternative Catalog Number: FBM-10-4047-5MG,FBM-10-4047-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-Benzyl-5-N-cyclopropyl-3-N-methyl-2-oxopyridine-3,5-dicarboxamide

Product Description

BD2 selective BET inhibitor

Product Properties

• Molecular Weight: 325.37
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [2088410-46-0]
• Formula: C18H19N3O3

Application Notes

• Application Notes: BET inhibitor 220-fold more selective for BD2 over BD1 (pIC50 BD2 = 7.1, BD1 = 4.8).1 It ameliorated collagen-induced arthritis in a rat model and imiquimod-induced psoriasis in a mouse model.2 GSK620 was also able to reduce hepatic fibrosis, steatosis, and inflammation in a mouse model of non-alcoholic steatohepatitis (NASH).