P053, CAS [[1022417-69-1]]

Produktübersicht

• Artikelname: P053, CAS [[1022417-69-1]]
• Artikelnummer: FBM-10-4060
• Hersteller Artikelnummer: 10-4060
• Alternativnummer: FBM-10-4060-5MG, FBM-10-4060-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3,5-Dimethyl-N-[4-(phenylmethyl)phenyl]-4-isoxazolesulfonamide

Produktbeschreibung

Protein phosphatase 5 inhibitor

Produkteigenschaften

• Molekulargewicht: 342.41
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Beige solid
• CAS Nummer: [1022417-69-1]
• Formel: C18H18N2O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: P053 is a selective inhibitor of protein phosphatase 5 (PP5) - IC50 = 706 nM.1 PP5 regulates signaling cascades that are responsible for tumor initiation, progression, and metastasis and is thus an interesting anticancer target. P053 induced apoptosis in 786-O renal carcinoma cells. Inhibition of PP5 by P053 prevents deactivation of the death effector protein FADD and activates the extrinsic apoptosis pathway complex II.