SIC5-6, CAS [[2410846-16-9]]

Produktübersicht

• Artikelname: SIC5-6, CAS [[2410846-16-9]]
• Artikelnummer: FBM-10-4075
• Hersteller Artikelnummer: 10-4075
• Alternativnummer: FBM-10-4075-10MG, FBM-10-4075-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3,3-(1-((4-Iodophenyl)sulfonyl)piperidine-4,4diyl)bis(1H-indole)

Produktbeschreibung

Separase inhibitor

Produkteigenschaften

• Molekulargewicht: 581.47
• Reinheit: 97% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [2410846-16-9]
• Formel: C27H24IN3O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Separase is a cysteine protease that triggers chromosome segregation during mitosis and is highly overexpressed in many cancers. SIC5-6 is an inhibitor of separase with no inhibition of the related protease caspase-1 in vitro. HeLa cells with dysregulated separase activity showed severe chromosome segregation defects on treatment with 30 µM SIC5-6 indicating a potential attractive new chemotherapeutic target.