NVS-STG2, CAS [[3030588-01-0]]

Produktübersicht

• Artikelname: NVS-STG2, CAS [[3030588-01-0]]
• Artikelnummer: FBM-10-4134
• Hersteller Artikelnummer: 10-4134
• Alternativnummer: FBM-10-4134-5MG,FBM-10-4134-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-((4-(2-(tert-Butyl)-5,5-dimethyl-1,3-dioxan-2-yl)benzyl)amino)-3-methoxybenzoic acid

Produktbeschreibung

Molecular glue STING agonist

Produkteigenschaften

• Molekulargewicht: 427.54
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [3030588-01-0]
• Formel: C25H33NO5

Anwendungsbeschreibung

• Anwendungsbeschreibung: NVS-STG2 is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 µM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.

Bilder

10-4134