NVS-STG2, CAS [[3030588-01-0]]

Product Overview

• Article Name: NVS-STG2, CAS [[3030588-01-0]]
• Biozol Catalog Number: FBM-10-4134
• Supplier Catalog Number: 10-4134
• Alternative Catalog Number: FBM-10-4134-5MG, FBM-10-4134-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-((4-(2-(tert-Butyl)-5,5-dimethyl-1,3-dioxan-2-yl)benzyl)amino)-3-methoxybenzoic acid

Product Description

Molecular glue STING agonist

Product Properties

• Molecular Weight: 427.54
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [3030588-01-0]
• Formula: C25H33NO5

Application Notes

• Application Notes: NVS-STG2 is a STING agonist that activates human STING by binding in a pocket between the transmembrane domains of neighboring STING dimers in a molecular glue-like manner (AC50 = 5.2 µM). Inactive with mouse STING. NVS-STG2 slowed tumor growth significantly in MC38 tumors inoculated into hSTING knock-in mice.