Alpelisib, CAS [[1217486-61-7]]

Produktübersicht

• Artikelname: Alpelisib, CAS [[1217486-61-7]]
• Artikelnummer: FBM-10-4167
• Hersteller Artikelnummer: 10-4167
• Alternativnummer: FBM-10-4167-5MG,FBM-10-4167-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: NVP-BYL719, BYL719

Produktbeschreibung

PI3K inhibitor

Produkteigenschaften

• Molekulargewicht: 441.47
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1217486-61-7]
• Formel: C19H22F3N5O2S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Alpelisib is a potent and selective (IC50s = 7.4 nM PI3Kalpha, 2.2 µM PI3Kß, 1.2 µM PI3KIdelta, 50-fold selectivity against 442 tested kinases) PI3Kalpha inhibitor.1 Approved for use in the treatment of HR(+), HER2(-), PIK3CA-mutated breast cancer. Alpelisib has been used in combination with various chemotherapeutics to treat ovarian2, colorectal3, kidney4, bladder5, and head and neck6 cancers.