Idasanutlin, CAS [[1229705-06-9]]

Produktübersicht

• Artikelname: Idasanutlin, CAS [[1229705-06-9]]
• Artikelnummer: FBM-10-4174
• Hersteller Artikelnummer: 10-4174
• Alternativnummer: FBM-10-4174-5MG,FBM-10-4174-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoic acid. Alternate Names: RG7388

Produktbeschreibung

p53-MDM2 inhibitor

Produkteigenschaften

• Molekulargewicht: 616.49
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1229705-06-9]
• Formel: C31H29Cl2F2N3O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Idasanutlin is a potent (IC50 = 6 nM) and selective inhibitor of MDM2, the primary negative regulator of p53.1 It blocks the p53-MDM2 interaction activating the p53 pathway leading to cell cycle arrest and apoptosis. Idasanutlin has displayed efficacy in the treatment of multiple cancers alone and in combination with other chemotherapeutics.2-6

Bilder

10-4174