SLC-0111, CAS [[178606-66-1]]

Produktübersicht

• Artikelname: SLC-0111, CAS [[178606-66-1]]
• Artikelnummer: FBM-10-4185
• Hersteller Artikelnummer: 10-4185
• Alternativnummer: FBM-10-4185-5MG, FBM-10-4185-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-(4-Fluorophenyl)-3-(4-sulfamoylphenyl)urea. Alternate Names: U-104

Produktbeschreibung

Carbonic anhydrase IX/XII inhibitor

Produkteigenschaften

• Molekulargewicht: 309.32
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [178606-66-1]
• Formel: C13H12FN3O3S

Anwendungsbeschreibung

• Anwendungsbeschreibung: SLC-0111 is a potent inhibitor of carbonic anhydrases IX and XII (Ki = 45 nM IX, 4.5 nM XII)1. Active in multiple cancer models2-5 and has displayed synergism with conventional chemotherapy6. SLC-0111 upregulated CD8+ T cells in murine pancreatic cancer models7 and improved responses to immune checkpoint inhibitors8.