PITSTOP2, CAS [[1332879-52-3]]

Produktübersicht

• Artikelname: PITSTOP2, CAS [[1332879-52-3]]
• Artikelnummer: FBM-10-4195
• Hersteller Artikelnummer: 10-4195
• Alternativnummer: FBM-10-4195-5MG,FBM-10-4195-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Clathrin-mediated endocystosis inhibitor

Produkteigenschaften

• Molekulargewicht: 473.36
• Reinheit: >98% by TLC NMR (Conforms)
• Formulierung: Pink solid
• CAS Nummer: [1332879-52-3]
• Formel: C20H13BrN2O3S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: PITSTOP2 inhibits clathrin-mediated endocytosis via blockade of endocytic ligand association with the clathrin terminal domain leading to clathrin coat assembly inhibition.1 It was able to cause a collapse of the nucleocytoplasmic permeability barrier and a reduction of Importin-ß binding.2 PITSTOP2 reduced viability in HeLa cells by trapping dividing cells in metaphase through loss of mitotic spindle integrity.3