V-9302, CAS [[1855871-76-9]]

Produktübersicht

• Artikelname: V-9302, CAS [[1855871-76-9]]
• Artikelnummer: FBM-10-4245
• Hersteller Artikelnummer: 10-4245
• Alternativnummer: FBM-10-4245-5MG, FBM-10-4245-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (2S)-2-Amino-4-[bis[[2-[(3-methylphenyl)methoxy]phenyl]methyl]amino]butanoic acid

Produktbeschreibung

Glutamine transport inhibitor

Produkteigenschaften

• Molekulargewicht: 538.69
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [1855871-76-9]
• Formel: C34H38N2O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Selective inhibitor of the alanine-serine-cysteine transporter 2 (ASCT2 or SLC1A5, IC50 = 9.0 µM rat and 9.6 µM human).1,2 It inhibited the uptake of both glutamine and possibly other amino acids in human cancer cells and reduced in vitro viability by at least 20% in more than half of 29 cancer cell lines screened.2 V-9302 decreased mTOR activity, elevated autophagy, and increased oxidative stress in multiple animal cancer models.2-5