Belzutifan, CAS [[1672668-24-4]]

Produktübersicht

• Artikelname: Belzutifan, CAS [[1672668-24-4]]
• Artikelnummer: FBM-10-4274
• Hersteller Artikelnummer: 10-4274
• Alternativnummer: FBM-10-4274-5MG, FBM-10-4274-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-[[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl]oxy]-5-fluorobenzonitrile. Alternate Names: PT2977, MK-6482

Produktbeschreibung

HIF-2alpha inhibitor

Produkteigenschaften

• Molekulargewicht: 383.34
• Reinheit: >98% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1672668-24-4]
• Formel: C17H12F3NO4S

Anwendungsbeschreibung

• Anwendungsbeschreibung: Belzutifan is a potent hypoxia-inducible factor 2alpha (HIF-2alpha) inhibitor (IC50 = 9 nM).1 Active in vivo in mouse and human studies of renal cell and non-renal cell carcinoma associated with VHL disease.1,2 An important toll for modulating the hypoxic tumor microenvironment.3 FDA approved for the treatment of von Hippel-Lindau associated diseases.