Belzutifan, CAS [[1672668-24-4]]

Product Overview

• Article Name: Belzutifan, CAS [[1672668-24-4]]
• Biozol Catalog Number: FBM-10-4274
• Supplier Catalog Number: 10-4274
• Alternative Catalog Number: FBM-10-4274-5MG, FBM-10-4274-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 3-[[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonyl-2,3-dihydro-1H-inden-4-yl]oxy]-5-fluorobenzonitrile. Alternate Names: PT2977, MK-6482

Product Description

HIF-2alpha inhibitor

Product Properties

• Molecular Weight: 383.34
• Purity: >98% by HPLC, NMR (Conforms)
• Form: White solid
• CAS Number: [1672668-24-4]
• Formula: C17H12F3NO4S

Application Notes

• Application Notes: Belzutifan is a potent hypoxia-inducible factor 2alpha (HIF-2alpha) inhibitor (IC50 = 9 nM).1 Active in vivo in mouse and human studies of renal cell and non-renal cell carcinoma associated with VHL disease.1,2 An important toll for modulating the hypoxic tumor microenvironment.3 FDA approved for the treatment of von Hippel-Lindau associated diseases.