ERGi-USU, CAS [[1147-56-4]]

Produktübersicht

• Artikelname: ERGi-USU, CAS [[1147-56-4]]
• Artikelnummer: FBM-10-4290
• Hersteller Artikelnummer: 10-4290
• Alternativnummer: FBM-10-4290-10MG, FBM-10-4290-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-(2-Thiazolylazo)-2-naphthol. Alternate Names: NSC139021

Produktbeschreibung

ERG inhibitor

Produkteigenschaften

• Molekulargewicht: 255.30
• Reinheit: 98% by TLC NMR (Confirms)
• Formulierung: Red or Orange solid
• CAS Nummer: [1147-56-4]
• Formel: C13H9N3OS

Anwendungsbeschreibung

• Anwendungsbeschreibung: ERGi-USU selectively inhibits the growth of ERG-positive VCaP prostate cancer cells, COLO320 colon cancer cells, KG-1 and MOLT-4 leukemia cells with minimal effect on ERG-negative cells or normal prostate or endothelial cells (IC50 = 169 nM for cell growth and 315 nM for ERG protein in VCaP cells). It selectively inhibits the kinase RIOK2 (Kd = 200 nM) causing disruption of ribosomal biogenesis and ribosomal stress.