HSL119

Produktübersicht

• Artikelname: HSL119
• Artikelnummer: FBM-10-4363
• Hersteller Artikelnummer: 10-4363
• Alternativnummer: FBM-10-4363-10MG, FBM-10-4363-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 3-((8-Amino-1,7-naphthyridin-5-yl)ethynyl)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide

Produktbeschreibung

HUNK inhibitor

Produkteigenschaften

• Molekulargewicht: 544.58
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Yellow solid
• Formel: C30H27F3N6O

Anwendungsbeschreibung

• Anwendungsbeschreibung: HSL119 is an inhibitor of the hormonally upregulated neu-associated kinase (HUNK), IC50 = 1.7 µM. It inhibits several other kinases including ABL1, BRAF, FLT3, and RET. HSL119 displays antitumor activity in several HER2/neu+ breast cancer models.