Indacaterol maleate, CAS [[753498-25-8]]

Produktübersicht

• Artikelname: Indacaterol maleate, CAS [[753498-25-8]]
• Artikelnummer: FBM-10-4371
• Hersteller Artikelnummer: 10-4371
• Alternativnummer: FBM-10-4371-10MG,FBM-10-4371-50MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: QAB149

Produktbeschreibung

ß2 adrenoceptor agonist/Splicing factor SRSF6 inhibitor

Produkteigenschaften

• Molekulargewicht: 508.57
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White to off-white solid
• CAS Nummer: [753498-25-8]
• Formel: C24H28N2O3C4H4O4

Anwendungsbeschreibung

• Anwendungsbeschreibung: Indacaterol maleate is a full agonist (pEC50 = 8.06) of the human ß2 adrenoceptor.1,2 Clinically important drug for the treatment of chronic obstructive pulmonary disease. Indacaterol blocked colorectal cancer progression in vitro (IC50 = 19.01 µM) and in vivo via inhibition of the splicing factor SRSF6 by binding to its RRM2 domain.3 It also blocked cell migration in metastatic breast cancer MDA-MB-231 cells by a similar mechanism.4