Indacaterol maleate, CAS [[753498-25-8]]

Product Overview

• Article Name: Indacaterol maleate, CAS [[753498-25-8]]
• Biozol Catalog Number: FBM-10-4371
• Supplier Catalog Number: 10-4371
• Alternative Catalog Number: FBM-10-4371-10MG,FBM-10-4371-50MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: QAB149

Product Description

ß2 adrenoceptor agonist/Splicing factor SRSF6 inhibitor

Product Properties

• Molecular Weight: 508.57
• Purity: >98% by HPLC NMR (Conforms)
• Form: White to off-white solid
• CAS Number: [753498-25-8]
• Formula: C24H28N2O3C4H4O4

Application Notes

• Application Notes: Indacaterol maleate is a full agonist (pEC50 = 8.06) of the human ß2 adrenoceptor.1,2 Clinically important drug for the treatment of chronic obstructive pulmonary disease. Indacaterol blocked colorectal cancer progression in vitro (IC50 = 19.01 µM) and in vivo via inhibition of the splicing factor SRSF6 by binding to its RRM2 domain.3 It also blocked cell migration in metastatic breast cancer MDA-MB-231 cells by a similar mechanism.4