SLF1081851, CAS [[2763730-97-6]]

Produktübersicht

• Artikelname: SLF1081851, CAS [[2763730-97-6]]
• Artikelnummer: FBM-10-4395
• Hersteller Artikelnummer: 10-4395
• Alternativnummer: FBM-10-4395-5MG,FBM-10-4395-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Sphingosine-1-phosphate transporter inhibitor

Produkteigenschaften

• Molekulargewicht: 379.79
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [2763730-97-6]
• Formel: C21H33N3OHCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: SLF1081851 is a sphingosine-1-phosphate transporter (Spns2) inhibitor. It inhibited sphingosine-1-phosphate (S1P) release in HeLa cells: IC50 = 1.93 µM. SLF1081851 is active in vivo and decreased lymphocyte counts and plasma S1P levels in mice and rats. Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.