SLF1081851, CAS [[2763730-97-6]]

Product Overview

• Article Name: SLF1081851, CAS [[2763730-97-6]]
• Biozol Catalog Number: FBM-10-4395
• Supplier Catalog Number: 10-4395
• Alternative Catalog Number: FBM-10-4395-5MG,FBM-10-4395-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien

Product Description

Sphingosine-1-phosphate transporter inhibitor

Product Properties

• Molecular Weight: 379.79
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [2763730-97-6]
• Formula: C21H33N3OHCl

Application Notes

• Application Notes: SLF1081851 is a sphingosine-1-phosphate transporter (Spns2) inhibitor. It inhibited sphingosine-1-phosphate (S1P) release in HeLa cells: IC50 = 1.93 µM. SLF1081851 is active in vivo and decreased lymphocyte counts and plasma S1P levels in mice and rats. Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.