SLB1122168, CAS [[2999629-17-1]]

Produktübersicht

• Artikelname: SLB1122168, CAS [[2999629-17-1]]
• Artikelnummer: FBM-10-4396
• Hersteller Artikelnummer: 10-4396
• Alternativnummer: FBM-10-4396-5MG, FBM-10-4396-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: (S)-6-Decyl-N-(pyrrolidine-3-ylmethyl)benzo[d]oxazol-2-amine hydrochloride

Produktbeschreibung

Spns2 inhibitor

Produkteigenschaften

• Molekulargewicht: 394.00
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: Off-white solid
• CAS Nummer: [2999629-17-1]
• Formel: C22H35N3OHCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: SLB1122168 is a potent (IC50 = 94 nM) second generation sphingosine-1-phosphate transporter Spinster Homolog 2 (Spns2) inhibitor. In vivo, it significantly reduced circulating lymphocyte counts but did not reduce plasma sphigosine-1-phosphate levels as with the first generation inhibitor SLF1081851 (Focus Cat 10-4395). Spns2 inhibitors represent potential alternative immunomodulatory agents to S1P receptor agonists as they are able in induce lymphopenia without drastic changes to systemic S1P levels or stimulating the S1P1-5 signaling pathway.