UR214-9, CAS [[2456263-31-1]]

Artikelnummer: FBM-10-4397
Artikelname: UR214-9, CAS [[2456263-31-1]]
Artikelnummer: FBM-10-4397
Hersteller Artikelnummer: 10-4397
Alternativnummer: FBM-10-4397-5MG, FBM-10-4397-25MG
Hersteller: Focus Biomolecules
Kategorie: Biochemikalien
Alternative Synonym: Chemical Name: N-(2,6-Dichloro-4-pyridinyl)-N-[2-fluoro-3-(trifluoromethyl)phenyl]urea
Septin inhibitor
Molekulargewicht: 368.11
Reinheit: >98% by HPLC NMR (Conforms)
Formulierung: White solid
CAS Nummer: [2456263-31-1]
Formel: C13H7Cl2F4N3O
Anwendungsbeschreibung: UR214-9 is an analog of Forchlorfenuron that was found to reduce HER2 and human epididymis protein 4 (HE4) levels and showed cytotoxicity against endometrial cancer via septin inhibition.1,2 It reduced ocular hypertension via disruption of the septin filament assembly in mice.3 UR214-9 induced mitochondrial fragmentation in macrophages in zebrafish larvae without altering mitochondrial mass leading to lytic cell death.4