UR214-9, CAS [[2456263-31-1]]

Product Overview

• Article Name: UR214-9, CAS [[2456263-31-1]]
• Biozol Catalog Number: FBM-10-4397
• Supplier Catalog Number: 10-4397
• Alternative Catalog Number: FBM-10-4397-5MG, FBM-10-4397-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-(2,6-Dichloro-4-pyridinyl)-N-[2-fluoro-3-(trifluoromethyl)phenyl]urea

Product Description

Septin inhibitor

Product Properties

• Molecular Weight: 368.11
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [2456263-31-1]
• Formula: C13H7Cl2F4N3O

Application Notes

• Application Notes: UR214-9 is an analog of Forchlorfenuron that was found to reduce HER2 and human epididymis protein 4 (HE4) levels and showed cytotoxicity against endometrial cancer via septin inhibition.1,2 It reduced ocular hypertension via disruption of the septin filament assembly in mice.3 UR214-9 induced mitochondrial fragmentation in macrophages in zebrafish larvae without altering mitochondrial mass leading to lytic cell death.4