Bedaquiline, CAS [[843663-66-1]]

Produktübersicht

• Artikelname: Bedaquiline, CAS [[843663-66-1]]
• Artikelnummer: FBM-10-4403
• Hersteller Artikelnummer: 10-4403
• Alternativnummer: FBM-10-4403-5MG,FBM-10-4403-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: TMC207, R207910

Produktbeschreibung

Antituberculosis / SARS-CoV2 3CLpro inhibitor

Produkteigenschaften

• Molekulargewicht: 555.50
• Reinheit: 99% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [843663-66-1]
• Formel: C32H31BrN2O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Bedaquiline is a clinically useful antituberculosis agent that is active (MICs 0.030 to 0.120 µg/mL) against multi-drug resistant strains.1 It interferes with mycobacterial energy metabolism via binding to the oligomeric subunit c (AtpE)2 and subunit 3 of ATP synthase inhibiting ATP production.4 Bedaquiline has recently been found to be an inhibitor (IC50 = 18.7 µM) of the SARS-CoV-2 main protease, 3CLpro.5