XL413HCl, CAS [[2062200-97-7]]

Produktübersicht

• Artikelname: XL413HCl, CAS [[2062200-97-7]]
• Artikelnummer: FBM-10-4414
• Hersteller Artikelnummer: 10-4414
• Alternativnummer: FBM-10-4414-5MG, FBM-10-4414-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 8-Chloro-2-[(2S)-pyrrolidin-2-yl]-3H-[1]benzofuro[3,2-d]pyrimidin-4-one hydrochloride

Produktbeschreibung

Cdc7 inhibitor/CRISPR enhancer

Produkteigenschaften

• Molekulargewicht: 326.18
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [2062200-97-7]
• Formel: C14H12ClN3O2HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: XL413 is a potent (IC50 = 4.8 nM) ATP-competitive inhibitor of the important DNA replication initiation kinase Cdc7 (DDK).1 It increases the efficiency of homology directed DNA repair in CRISPR-Cas9 gene editing.2 XL413 acted synergistically with other chemotherapy agents in various cancer models.3-5