HPI-1, CAS [[599150-20-6]]

Produktübersicht

• Artikelname: HPI-1, CAS [[599150-20-6]]
• Artikelnummer: FBM-10-4522
• Hersteller Artikelnummer: 10-4522
• Alternativnummer: FBM-10-4522-5MG,FBM-10-4522-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Hedgehog pathway inhibitor

Produkteigenschaften

• Molekulargewicht: 463.52 (anhydrous)
• Reinheit: >98% (TLC: 80% Ethyl acetate/hexanes, Rf = 0.37)
• Formulierung: Yellow solid
• CAS Nummer: [599150-20-6]
• Formel: C27H29NO6xH20

Anwendungsbeschreibung

• Anwendungsbeschreibung: HPI-1 is a Hedgehog pathway inhibitor acting downstream of Smo and independently of PKA, PI3K and MAPK. It can suppress Hh pathway activation induced by loss of Su(fu) or Gli overexpression. Inhibits both endogenous and exogenous Gli1/Gli2 activity. IC50s range from 0.2 to 6 µM for various cell-based assays.