UNC1999, CAS [[1431612-23-5]]

Produktübersicht

• Artikelname: UNC1999, CAS [[1431612-23-5]]
• Artikelnummer: FBM-10-4542
• Hersteller Artikelnummer: 10-4542
• Alternativnummer: FBM-10-4542-5MG, FBM-10-4542-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[(6-methyl-2-oxo-4-propyl-1H-pyridin-3-yl)methyl]-1-propan-2-yl-6-[6-(4-propan-2-ylpiperazin-1-yl)pyridin-3-yl]indazole-4-carboxamide

Produktbeschreibung

Methyltransferase inhibitor

Produkteigenschaften

• Molekulargewicht: 569.74
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1431612-23-5]
• Formel: C33H43N7O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: UNC1999 is an orally bioavailable, highly selective inhibitor of both wild-type and mutant EZH1 and EZH2 lysine methyltransferases (IC50s = 45 nM and 2 nM respectively).1 Inhibition of EZH2 with UNC1999 enhanced the efficacy of gefitinib in suppressing the proliferation of colon cancer cells