gamma-L-Glutamyl-p-nitroanilide HCl, CAS [[67953-08-6]]

Produktübersicht

• Artikelname: gamma-L-Glutamyl-p-nitroanilide HCl, CAS [[67953-08-6]]
• Artikelnummer: FBM-10-4568
• Hersteller Artikelnummer: 10-4568
• Alternativnummer: FBM-10-4568-100MG,FBM-10-4568-250MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: GPNA

Produktbeschreibung

L-glutamine uptake inhibitor and gamma-glutamyl transpeptidase substrate

Produkteigenschaften

• Molekulargewicht: 303.70
• Reinheit: 98%
• Formulierung: Off-white solid
• CAS Nummer: [67953-08-6]
• Formel: C11H13N3O5 HCl

Anwendungsbeschreibung

• Anwendungsbeschreibung: L-gamma-Glutamyl-p-nitroanilide (GPNA) is a substrate for gamma-glutamyl transpeptidase. GPNA is used for the determination of gamma-glutamyl transpeptidase hydrolytic activity via spectrophotometric monitoring of p-nitroaniline released by the action of the enzyme on GPNA.1 GPNA has also been shown to be an inhibitor of glutamine uptake - solute-linked carrier family A1 member 5 (SLC1A5)2 Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that activates mTOR and is, thus, an interesting cancer chemotherapy target.3