SR9243, CAS [[1613028-81-1]]

Produktübersicht

• Artikelname: SR9243, CAS [[1613028-81-1]]
• Artikelnummer: FBM-10-4579
• Hersteller Artikelnummer: 10-4579
• Alternativnummer: FBM-10-4579-5MG, FBM-10-4579-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3-(methylsulfonyl)[1,1-biphenyl]-4-yl]methyl]-benzenesulfonamide

Produktbeschreibung

LXR inverse agonist

Produkteigenschaften

• Molekulargewicht: 626.62
• Reinheit: >98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1613028-81-1]
• Formel: C31H32BrNO4S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: SR9243 is an LXR inverse agonist that significantly inhibits the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression.1 Induces apoptosis in a variety of cancer cell types including SW620 (IC50 = 40 nM), HT-29 (IC50 = 104 nM), DU-145 (IC50 = 15 nM), PC-3 (IC50 = 61 nM), NCI-H23 (IC50 = 72 nM), HOP-62 (IC50 = 26 nM) and MIAPACA-2 (IC50 = 18 nM). SR9243 is able to promote apoptotic cancer cell death without adversely affecting non-malignant cells.