SR9243, CAS [[1613028-81-1]]

Product Overview

• Article Name: SR9243, CAS [[1613028-81-1]]
• Biozol Catalog Number: FBM-10-4579
• Supplier Catalog Number: 10-4579
• Alternative Catalog Number: FBM-10-4579-5MG, FBM-10-4579-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-[2-(3-Bromophenyl)ethyl]-2,4,6-trimethyl-N-[[3-(methylsulfonyl)[1,1-biphenyl]-4-yl]methyl]-benzenesulfonamide

Product Description

LXR inverse agonist

Product Properties

• Molecular Weight: 626.62
• Purity: >98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1613028-81-1]
• Formula: C31H32BrNO4S2

Application Notes

• Application Notes: SR9243 is an LXR inverse agonist that significantly inhibits the Warburg effect and lipogenesis by reducing glycolytic and lipogenic gene expression.1 Induces apoptosis in a variety of cancer cell types including SW620 (IC50 = 40 nM), HT-29 (IC50 = 104 nM), DU-145 (IC50 = 15 nM), PC-3 (IC50 = 61 nM), NCI-H23 (IC50 = 72 nM), HOP-62 (IC50 = 26 nM) and MIAPACA-2 (IC50 = 18 nM). SR9243 is able to promote apoptotic cancer cell death without adversely affecting non-malignant cells.