Gimeracil, CAS [[103766-25-2]]

Produktübersicht

• Artikelname: Gimeracil, CAS [[103766-25-2]]
• Artikelnummer: FBM-10-4601
• Hersteller Artikelnummer: 10-4601
• Alternativnummer: FBM-10-4601-25MG, FBM-10-4601-100MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 5-Chloro-4-hydroxypyridine-2(1H)-one

Produktbeschreibung

Dihydropyrimidine dehydrogenase inhibitor

Produkteigenschaften

• Molekulargewicht: 145.54
• Reinheit: 98% by HPLC, NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [103766-25-2]
• Formel: C5H4ClNO2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Gimeracil is a dihydropyrimidine dehydrogenase (DPD) inhibitor. DPD is involved in the degradation of pyrimidine-based chemotherapeutic drugs such as 5-fluorouracil (5-FU). Gimeracil is used along with 5-FU or Tegafur to prolong circulating concentrations of the drugs.1,2 Gimeracil has also been shown to act as a radiosensitizer via inhibition of homologous recombination in the repair of DNA double strand breaks.3