CDN1163, CAS [[892711-75-0]]

Produktübersicht

• Artikelname: CDN1163, CAS [[892711-75-0]]
• Artikelnummer: FBM-10-4627
• Hersteller Artikelnummer: 10-4627
• Alternativnummer: FBM-10-4627-5MG, FBM-10-4627-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide

Produktbeschreibung

SERCA activator

Produkteigenschaften

• Molekulargewicht: 320.39
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [892711-75-0]
• Formel: C20H20N2O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: Allosteric activator of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).1,2 It lowered fasting glucose levels, improved glucose tolerance, and ameliorated hepatitis steatosis in ob/ob mice.1 CDN1163 also rescued neurons from ER-stress-induced cell death in vitro and displayed significant efficacy in a rat 6-hydroxydopamine (6-OHDA) model of Parkinsons disease.2 It reduced age-related muscle atrophy and weakness in a C57BL/6J mice.3 CDN1163 decreased inflammatory cytokines and chemokines and attenuated mitochondrial dysfunction in Influenza A infected H1395 cells.4