CDN1163, CAS [[892711-75-0]]

Product Overview

• Article Name: CDN1163, CAS [[892711-75-0]]
• Biozol Catalog Number: FBM-10-4627
• Supplier Catalog Number: 10-4627
• Alternative Catalog Number: FBM-10-4627-5MG, FBM-10-4627-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide

Product Description

SERCA activator

Product Properties

• Molecular Weight: 320.39
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [892711-75-0]
• Formula: C20H20N2O2

Application Notes

• Application Notes: Allosteric activator of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA).1,2 It lowered fasting glucose levels, improved glucose tolerance, and ameliorated hepatitis steatosis in ob/ob mice.1 CDN1163 also rescued neurons from ER-stress-induced cell death in vitro and displayed significant efficacy in a rat 6-hydroxydopamine (6-OHDA) model of Parkinsons disease.2 It reduced age-related muscle atrophy and weakness in a C57BL/6J mice.3 CDN1163 decreased inflammatory cytokines and chemokines and attenuated mitochondrial dysfunction in Influenza A infected H1395 cells.4