PF-9366, CAS [[72882-78-1]]

Produktübersicht

• Artikelname: PF-9366, CAS [[72882-78-1]]
• Artikelnummer: FBM-10-4635
• Hersteller Artikelnummer: 10-4635
• Alternativnummer: FBM-10-4635-5MG,FBM-10-4635-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien

Produktbeschreibung

Methionine adenosyltransferase 2A inhibitor

Produkteigenschaften

• Molekulargewicht: 350.85
• Reinheit: 98% by TLC NMr (Conforms)
• Formulierung: Beige solid
• CAS Nummer: [72882-78-1]
• Formel: C20H19ClN4

Anwendungsbeschreibung

• Anwendungsbeschreibung: PF-9366 is an allosteric inhibitor (IC50 = 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1 It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50s of 1.2 µM and 225 nM respectively.