NS 1619, CAS [[153587-01-0]]

Produktübersicht

• Artikelname: NS 1619, CAS [[153587-01-0]]
• Artikelnummer: FBM-10-4643
• Hersteller Artikelnummer: 10-4643
• Alternativnummer: FBM-10-4643-5MG, FBM-10-4643-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 1-(2-Hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole-2(3H)-one

Produktbeschreibung

Selective KCa1.1 activator

Produkteigenschaften

• Molekulargewicht: 362.23
• Reinheit: 98% by TLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [153587-01-0]
• Formel: C15H8F6N2O2

Anwendungsbeschreibung

• Anwendungsbeschreibung: NS 1619 is a selective activator of large conductance Ca(2+)-dependent potassium channels (BKCa or KCa1.1).1,2 It was able to increase blood-brain tumor barrier permeability in rat brain tumor models.3,4 NS 1619 inhibited proliferation and induced apoptosis in A2780 ovarian cancer cells.5 Displays cardioprotective effects in an ischemia-reperfusion model6 and neuroprotective effects in a traumatic brain injury model7.