Chemical Name: 1-Phenyl-3,3-bis(pyridine-4-ylmethyl)indolin-2-one dihydrochloride. Alternate Names: DuP 996
Kv7 blocker
Molekulargewicht:
464.39
Reinheit:
98% by HPLC NMR (Conforms)
Formulierung:
Off-white solid
CAS Nummer:
[113168-57-3]
Formel:
C26H21N3O2HCl
Anwendungsbeschreibung:
Linopirdine increases acetylcholine release and improves performance in animal models of learning and memory via blockade of Kv7 (KCNQ) voltage-gated potassium channels.1-3 Linopirdine is a state-dependent blocker favoring activated single subunits of the channel.4 It has also been shown to act as an agonist of TRPV1.5
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