Linopirdine dihydrochloride, CAS [[113168-57-3]]

Product Overview

• Article Name: Linopirdine dihydrochloride, CAS [[113168-57-3]]
• Biozol Catalog Number: FBM-10-4654
• Supplier Catalog Number: 10-4654
• Alternative Catalog Number: FBM-10-4654-5MG, FBM-10-4654-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 1-Phenyl-3,3-bis(pyridine-4-ylmethyl)indolin-2-one dihydrochloride. Alternate Names: DuP 996

Product Description

Kv7 blocker

Product Properties

• Molecular Weight: 464.39
• Purity: 98% by HPLC NMR (Conforms)
• Form: Off-white solid
• CAS Number: [113168-57-3]
• Formula: C26H21N3O2HCl

Application Notes

• Application Notes: Linopirdine increases acetylcholine release and improves performance in animal models of learning and memory via blockade of Kv7 (KCNQ) voltage-gated potassium channels.1-3 Linopirdine is a state-dependent blocker favoring activated single subunits of the channel.4 It has also been shown to act as an agonist of TRPV1.5