VU0810464, CAS [[2126040-21-7]]

Produktübersicht

• Artikelname: VU0810464, CAS [[2126040-21-7]]
• Artikelnummer: FBM-10-4662
• Hersteller Artikelnummer: 10-4662
• Alternativnummer: FBM-10-4662-5MG, FBM-10-4662-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 2-(3-Chloro-4-fluorophenyl)-N-(2-cyclohexyl-5-methylpyrazol-3-yl)acetamide

Produktbeschreibung

Kir3 activator

Produkteigenschaften

• Molekulargewicht: 349.83
• Reinheit: >98% by TLC (NMR Conforms)
• Formulierung: White solid
• CAS Nummer: [2126040-21-7]
• Formel: C18H21ClFN3O

Anwendungsbeschreibung

• Anwendungsbeschreibung: VU0810464 is potent (Kir3.1/3.2, GIRK1/2 EC50 = 165 nM) activator of G protein-gated inwardly-rectifying potassium channels (Kir3, GIRK).1,2 Displays selectivity for Kir3.1/3.2 versus Kir3.1/3.4 as well as selectivity for neuronal versus cardiac Kir3 channels. VU0810464 reduced stress-induced hyperthermia but not anxiety-related behavior in mice.