FIN56, CAS [[1083162-61-1]]

Produktübersicht

• Artikelname: FIN56, CAS [[1083162-61-1]]
• Artikelnummer: FBM-10-4666
• Hersteller Artikelnummer: 10-4666
• Alternativnummer: FBM-10-4666-5MG, FBM-10-4666-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: N2,N7-Dicyclohexyl-9-hydroxyiminofluorene-2,7-disulfonamide. Alternate Names: Ferroptosis inducing 56

Produktbeschreibung

Squalene synthase activator / GPX4 degradation

Produkteigenschaften

• Molekulargewicht: 517.66
• Reinheit: 98% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [1083162-61-1]
• Formel: C25H31N3O5S2

Anwendungsbeschreibung

• Anwendungsbeschreibung: FIN56 is a novel inducer of ferroptosis acting via degradation of GPX4 and activation of squalene synthase (leading to CoQ10 depletion, a compound which inhibits ferroptosis via an unknown mechanism).1 FIN56 inhibited glioblastoma growth in vitro and in vivo via induction of ferroptosis as well as lysosomal membrane permeabilization.2