FIN56, CAS [[1083162-61-1]]

Product Overview

• Article Name: FIN56, CAS [[1083162-61-1]]
• Biozol Catalog Number: FBM-10-4666
• Supplier Catalog Number: 10-4666
• Alternative Catalog Number: FBM-10-4666-5MG, FBM-10-4666-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N2,N7-Dicyclohexyl-9-hydroxyiminofluorene-2,7-disulfonamide. Alternate Names: Ferroptosis inducing 56

Product Description

Squalene synthase activator / GPX4 degradation

Product Properties

• Molecular Weight: 517.66
• Purity: 98% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [1083162-61-1]
• Formula: C25H31N3O5S2

Application Notes

• Application Notes: FIN56 is a novel inducer of ferroptosis acting via degradation of GPX4 and activation of squalene synthase (leading to CoQ10 depletion, a compound which inhibits ferroptosis via an unknown mechanism).1 FIN56 inhibited glioblastoma growth in vitro and in vivo via induction of ferroptosis as well as lysosomal membrane permeabilization.2