Chemical Name: N-[(3-Chlorophenyl)methyl]spiro[1,4-dihydroquinoxaline-3,4-piperidine]-2-amine
Ferroptosis inhibitor
Molekulargewicht:
340.85
Reinheit:
98% by HPLC NMR (Conforms)
Formulierung:
White or off-white solid
CAS Nummer:
[950455-15-9]
Formel:
C19H21ClN4
Anwendungsbeschreibung:
Liproxstatin-1 is an inhibitor of ferroptosis (IC50 = 22 nM).1 It was able to mitigate tissue injury in a mouse model of hepatic ischemia/reperfusion injury.1 It protected mouse myocardium against ischemia/reperfusion injury via a decrease in VDAC1 and restoration of GPX4 levels.2 Liproxstatin-1s mechanism of activity has been attributed to its activity as a radical-trapping antioxidant.3
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