Liproxstatin-1, CAS [[950455-15-9]]

Product Overview

• Article Name: Liproxstatin-1, CAS [[950455-15-9]]
• Biozol Catalog Number: FBM-10-4670
• Supplier Catalog Number: 10-4670
• Alternative Catalog Number: FBM-10-4670-5MG, FBM-10-4670-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: N-[(3-Chlorophenyl)methyl]spiro[1,4-dihydroquinoxaline-3,4-piperidine]-2-amine

Product Description

Ferroptosis inhibitor

Product Properties

• Molecular Weight: 340.85
• Purity: 98% by HPLC NMR (Conforms)
• Form: White or off-white solid
• CAS Number: [950455-15-9]
• Formula: C19H21ClN4

Application Notes

• Application Notes: Liproxstatin-1 is an inhibitor of ferroptosis (IC50 = 22 nM).1 It was able to mitigate tissue injury in a mouse model of hepatic ischemia/reperfusion injury.1 It protected mouse myocardium against ischemia/reperfusion injury via a decrease in VDAC1 and restoration of GPX4 levels.2 Liproxstatin-1s mechanism of activity has been attributed to its activity as a radical-trapping antioxidant.3