Luminespib, CAS [[747412-49-3]]

Produktübersicht

• Artikelname: Luminespib, CAS [[747412-49-3]]
• Artikelnummer: FBM-10-4672
• Hersteller Artikelnummer: 10-4672
• Alternativnummer: FBM-10-4672-5MG, FBM-10-4672-25MG
• Hersteller: Focus Biomolecules
• Kategorie: Biochemikalien
• Alternative Synonym: Chemical Name: 5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide. Alternate Names: NVP-AUY922, VER-52296

Produktbeschreibung

HSP90 inhibitor

Produkteigenschaften

• Molekulargewicht: 465.54
• Reinheit: >99% by HPLC NMR (Conforms)
• Formulierung: White solid
• CAS Nummer: [747412-49-3]
• Formel: C26H31N3O5

Anwendungsbeschreibung

• Anwendungsbeschreibung: Luminespib is a potent inhibitor (IC50 = 21 nM) of HSP90.1 It is active against various human tumor xenograft models acting via several processes including cytostasis, apoptosis, invasion, and angiogenesis.2,3 Luminespib enhances tumor susceptibility to T-cell-based immunotherapy by re-invigorating the cancer-immunity cycle in NANOG+ cancer cells.4 It also acts as a radiosensitizer against various tumor cells.5-7