Luminespib, CAS [[747412-49-3]]

Product Overview

• Article Name: Luminespib, CAS [[747412-49-3]]
• Biozol Catalog Number: FBM-10-4672
• Supplier Catalog Number: 10-4672
• Alternative Catalog Number: FBM-10-4672-5MG, FBM-10-4672-25MG
• Manufacturer: Focus Biomolecules
• Category: Biochemikalien
• Alternative Names: Chemical Name: 5-(2,4-Dihydroxy-5-propan-2-ylphenyl)-N-ethyl-4-[4-(morpholin-4-ylmethyl)phenyl]-1,2-oxazole-3-carboxamide. Alternate Names: NVP-AUY922, VER-52296

Product Description

HSP90 inhibitor

Product Properties

• Molecular Weight: 465.54
• Purity: >99% by HPLC NMR (Conforms)
• Form: White solid
• CAS Number: [747412-49-3]
• Formula: C26H31N3O5

Application Notes

• Application Notes: Luminespib is a potent inhibitor (IC50 = 21 nM) of HSP90.1 It is active against various human tumor xenograft models acting via several processes including cytostasis, apoptosis, invasion, and angiogenesis.2,3 Luminespib enhances tumor susceptibility to T-cell-based immunotherapy by re-invigorating the cancer-immunity cycle in NANOG+ cancer cells.4 It also acts as a radiosensitizer against various tumor cells.5-7